The preaching friars took possession of the place in 1668, when the order of the Jesuits was suppressed, not to be confused with that of the Jesuits, located in the Cannaregio District.
The religious order was suppressed by Pope Clement IX, after the poor Gesuati had built the church of San Girolamo and a large convent, for the degrowth of the order and its internal crisis. Their assets were taken from the Serenissima, to finance the violent battle of the Venetians against the Ottoman Turks in the Mediterranean.
The brightest period of the Jesuit order was in the fifteenth century, during which numerous convents of the Veneto, Rome, Milan, Cremona, Brescia and even Toulouse were part of the clerical congregation. The current church was built in 1743 by Giorgio Massari and decorated with exuberant baroque and rococo elements.
The imposing external facade reflects that of the church of the Redeemer in Giudecca. Inside, on the ceiling, we find the frescoes by Gianbattista Tiepolo depicting events from the life of San Domenico, The institution of the Rosary, The Glory of San Domenico and The Madonna appears in San Domenico, painted between 1737 and 1739.
Along the left nave, moreover, we find The Crucifixion by Tintoretto and finally San Domenico and Visione dei Santi Ludovico Bertrando, Vincenzo Ferreri and Giacinto. To further embellish the interior and to make it a concrete example of the state of the art of Venice of that period, are the works of Giambattista Piazzetta, Sebastiano Ricci and Gianmaria Morlaiter, which left precious masterpieces.
